In the role of anatomic pathologist within NIBR’s Translational Medicine team you will provide expertise to research and preclinical safety studies through well-written reports that accurately reflect data derived from standard and innovative anatomic pathology endpoints as well as investigative biomarkers and molecular assessments. In conjunction with the study teams, you will contribute an integrated assessment of the significance of study findings to human safety within regulatory submission packages. You will also actively participate in the global drug development process through contributions as a Project Pathologist on assigned drug targets and also has the opportunity to serve as the safety assessment expert on project teams. In addition, you will work collaboratively within our pathology and investigative safety teams to build our scientific and technical expertise in translational biomarkers and technologies used to support safety studies and in-vivo safety models.
Your major accountabilities will include but not be limited to:
- Effectively assess for pharmacological and toxicological effects of small molecules and biologics in preclinical studies, with a focus on anatomic pathology and pathology peer review.
- Collaborate with global team of pathologists and other scientists in design of preclinical safety studies and interpretation and communication of study findings, including the impact of the data on the safety profile and clinical development.
- Provide oversight and/or pathology peer review of protocols, data, and reports generated at contract laboratories and maintain effective relationships with CRO pathologists, scientists, and technical staff to ensure high quality, on-time reporting.
- Drive scientific and technical support for identification, development, qualification, and validation of translational biomarkers and pathology endpoints through collaboration with internal and external expert working groups.
- Serve as Project Pathologist on assigned compounds, targets, and therapeutic areas.
- Opportunity to participate as safety assessment expert on global drug development project teams
- Doctor of Veterinary Medicine or equivalent
- Board Certification in Anatomic Pathology by European/American College of Veterinary Pathologists (ECVP or ACVP)
- Preferred: PhD in a biological science
- Experience in toxicological pathology. Preferred: Experience in biologics, gene and cell therapy and emerging/novel modalities application in safety assessment, preferably within pharmaceutical/biotech or contract research organization
- Good understanding of the drug development process, preferably including experience working directly on drug development project teams and Regulatory interactions and submissions
- Excellent verbal and written communication skills
- Ability to work cross-functionally within a team and matrix environment
- Experience with GLP regulations and peer review
- Experience with digital pathology systems
Commitment to Diversity & Inclusion:
Novartis embraces diversity, equal opportunity and inclusion. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration, and empowers our people to unleash their full potential.
Join our Novartis Network:
If this role is not suitable to your experience or career goals but you wish to stay connected to learn more about Novartis and our career opportunities, join the Novartis Network here: https://talentnetwork.novartis.com/network
769 million lives were touched by Novartis medicines in 2020, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.
We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.
We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what’s possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!
- Some restrictions on flexible working options may apply and will be discussed during interview if applicable.