In Roche´s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
The Early Biomarker Development Oncology (EBDO) Team is responsible for the identification and validation of candidate molecular biomarkers used for the demonstration of pharmacodynamic effects and mechanism of action, as well as for response prediction and patient selection/stratification. The EBDO Team supports the whole oncology portfolio and closely interacts with Discovery and Early Clinical Development.
As a Project Pathologist, you are part of the Digital Pathology team within EBDO and are responsible for developing the tissue biomarker strategy across several Oncology projects. You are an expert on tissue analysis and Digital Pathology approaches. You provide scientific guidance and generate key insights from tissue data to support drug development decision-making.
You are part of a cross-functional Digital Pathology team to be at the forefront of tissue biomarker research for Oncology
You are an expert on the analysis of tumour tissue and its application to Drug Development, including Digital Pathology
You drive key biomarker and pathology capabilities across the Discovery and Early Clinical Development Oncology pipeline (Phase 0, 1, 1b, 2)
You work at the project and portfolio level with responsibility for a portfolio of projects in the field of Immuno-oncology and Targeted therapies: tissue biomarker strategy design and implementation for the projects and portfolio area under your responsibility, reverse translation strategy design and implementation to analyze biomarker data, generate insights relevant to the portfolio
You developed deep expertise through study analysis and thorough knowledge of literature
You lead external academic partnerships as they relate to tissue biomarkers and/or digital pathology.
You are an experienced MD anatomic pathologist with 5+ years of postgraduate experience
You bring a minimum of 5 years of previous R&D experience
You bring experience in tissue biomarkers such as discovering/developing insights from the analysis of tumours and tissues into testable clinical hypotheses.
You also have experience in leading scientific teams and direct reports.
You are experienced in supervising, exploring, developing and analyzing tissue analysis techniques such as immunohistochemistry, multiplex immunofluorescence, image analysis and spatial-omics approaches.
You bring experience and interest in developing cutting-edge digital pathology approaches.
Background in cancer biology, cancer genetics and immunology
Expertise in tissue biomarkers, including digital pathology and image analysis in an R&D setting, including as project team lead
Provide mentorship and/or direct oversight of junior pathologists, Postdocs, or PhD students
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We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
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Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.
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