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November 2023

Case Of The Month | November 2023 | Colour Dilution Alopecia

2023-11-09T08:34:29+00:00

Here is a case from a 3-year-old male Doberman that was exhibiting generalised dry dermatitis and alopecia over the trunk and had been non-responsive to conventional, medical treatment. A series of biopsies were examined digitally here at NationWide Laboratories which showed mild changes within the epidermis including irregularly spaced, hyperpigmented basal epithelial cells and some pigmentary incontinence. Within the dermis, there was very noticeable follicular dysplasia and dense clumps of melanin pigment within the hair bulbs and follicles and even in the hair shafts, including enlarged melanomacrophages surrounding the base of the hair follicles. Overall, within the sections, the hair follicles are atrophied. There were minimal inflammatory cells throughout the sections. These histological features are consistent with chronic pigmentary intrafollicular and intraepidermial melanin clumping and pigmentary incontinence that is consistent with colour dilute/colour mutatnt alopecia or black hair follicular dysplasia and are observed in colour dilute dogs (e.g., blue or fawn colours). The follicular dysplasia often leads to poor hair coat quality and variably alopecia, such as that reported in this case. Hair loss is usually most severe on the trunk, especially dorsally. Secondary bacterial infection can sometimes be seen. This form of colour dilution alopecia is commonly seen in the Doberman Pinscher. As such, this is a classic case and the use of digital pathology allows us to both accurately diagnose the condition, whilst effectively sharing the key histological findings to our trainee pathologists and students. The ability to pan the whole slide image also allows us to quickly make judgements of the most important pathology and hone our attentions to these changes.

Case Of The Month | November 2023 | Colour Dilution Alopecia2023-11-09T08:34:29+00:00

The Digital Pathologists’ Playbook™ by Lumea

2023-11-08T10:29:31+00:00

Get Lumea's free Digital Pathologists’ Playbook, your step-by-step guide to going digital. The booklet includes step-by-step instructions, vendor lists, specs to keep in mind, how to get a return on investment, and must-attend annual events that will keep you up-to-date on the latest news and tech.

The Digital Pathologists’ Playbook™ by Lumea2023-11-08T10:29:31+00:00

Pathways to Success in Outsourced R&D: How CROs Become More Indispensable for Sponsors via Digital Pathology

2023-11-07T15:15:34+00:00

In the pharmaceutical industry, all companies, regardless of their size or area of focus, aim to optimize returns on approved therapies, streamline development processes and minimize trial failures. With the industry poised for further growth and an influx of innovative therapeutics and cell and gene therapies, selecting the most suitable Contract Research Organization (CRO) to form a partnership becomes mission critical.

Pathways to Success in Outsourced R&D: How CROs Become More Indispensable for Sponsors via Digital Pathology2023-11-07T15:15:34+00:00

Making Real-Time Brain Tumor Diagnoses a Reality: AI System Classifies Gliomas From Cryosection Images

2025-06-26T15:52:30+00:00

In a recent study, researchers at Harvard Medical School, Perelman School of Medicine at the University of Pennsylvania, and Cedars-Sinai Medical Center developed a machine learning method for cryosection pathology. The proposed model allowed them to accurately classify gliomas using digital images of cryosection samples during surgery, demonstrating the potential of AI for enabling real-time, intraoperative brain cancer diagnosis.

Making Real-Time Brain Tumor Diagnoses a Reality: AI System Classifies Gliomas From Cryosection Images2025-06-26T15:52:30+00:00

October 2023

New £100 Million Fund to Revolutionise Cancer Diagnostics Using AI

2023-10-31T13:41:47+00:00

In an ambitious move to redefine cancer diagnostics and treatment, the UK Prime Minister has announced a transformative £100 million fund designed to accelerate the integration of Artificial Intelligence (AI) in life sciences, with a particular emphasis on cancer diagnostics.

New £100 Million Fund to Revolutionise Cancer Diagnostics Using AI2023-10-31T13:41:47+00:00

Getting Underway At Pathology Visions 2023

2023-10-29T13:58:59+00:00

This October, as the vibrant city of Orlando plays host to Pathology Visions 2023 at the prestigious Hyatt Regency, we at Pathology News are filled with anticipation and excitement. From October 29th to 31st, this event, proudly presented by the Digital Pathology Association, promises to be a cornerstone for the latest in digital pathology, bringing together the brightest minds and innovators in the field.

Getting Underway At Pathology Visions 20232023-10-29T13:58:59+00:00

U.S. FDA Grants Paige Breakthrough Device Designation for Cancer Detection in Breast Lymph Nodes

2023-10-27T14:03:20+00:00

Paige, a global leader in end-to-end digital pathology solutions and clinical AI applications that assist in diagnosing cancer, announced today that the U.S Food and Drug Administration (FDA) has granted Breakthrough Device Designation for Paige Lymph Node, an AI application used to detect breast cancer metastases in lymph node tissue. Paige Lymph Node is the first AI application of its kind to receive Breakthrough Device Designation from the FDA.

U.S. FDA Grants Paige Breakthrough Device Designation for Cancer Detection in Breast Lymph Nodes2023-10-27T14:03:20+00:00

Leica Biosystems Launches Joint Solution with Paige to Accelerate Adoption of Digital Pathology and AI

2023-10-24T16:10:26+00:00

Leica Biosystems, a global leader in anatomic pathology, and Paige, a leader in digital pathology software and diagnostic AI applications, previously announced a partnership to create an integrated solution, to expand access to accelerate adoption of digital pathology and artificial intelligence (AI). The companies are now launching their integrated solution at the Digital Pathology Association’s (DPA) Pathology Visions 2023 conference in Orlando, Florida.

Leica Biosystems Launches Joint Solution with Paige to Accelerate Adoption of Digital Pathology and AI2023-10-24T16:10:26+00:00

Proscia Achieves ISO 27001 Security Certification

2023-10-24T15:42:46+00:00

Proscia®, a leading provider of digital and computational pathology solutions, has earned ISO 27001 certification. This certification demonstrates the company’s compliance with one of the best-known information security management standards, giving customers added confidence in its products.

Proscia Achieves ISO 27001 Security Certification2023-10-24T15:42:46+00:00

Fast Forward: Digital Pathology Enhances Speed of Slide Review

2023-10-20T10:16:13+00:00

It’s time to dispel the myth that slide review is slow with digital pathology, says consultant pathologist Dr. Rebecca Millican-Slater, the Lead Clinician for Cellular Pathology at the St. James’s University Hospital, Leeds, UK.

Fast Forward: Digital Pathology Enhances Speed of Slide Review2023-10-20T10:16:13+00:00
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