The recent advances in single-cell technologies have facilitated the emergence of spatial genomics and spatial transcriptomics technologies. Combing whole slide imaging with molecular technologies, researchers can see all of their data within the spatial context of the tissue.
Recent advances in Raman spectroscopy, including stimulated Raman scattering and its integration with high-resolution microscopes, have allowed the utilization of Raman spectroscopy for the analysis of single cells and tissues, opening a new avenue for modern pathology.
Results from AI study showed 100% sensitivity and reduced time to diagnosis by an estimated 65.5%, with potential to improve pathologists’ workflow in a real-world environment.
Rapid diagnosis of infectious disease is a prerequisite at any time and especially so during the current coronavirus pandemic. Traditional molecular methods such as the polymerase chain reaction (PCR) or immunosensing are frequently used for viral detection. These techniques can efficiently detect and assess viral infections, but demand time, expertise, and several pre-treatments. Advanced nanopore sensing has [...]
Paige, a global leader in AI-based digital diagnostics, and Leica Biosystems, a globally recognized cancer diagnostics and workflow solution leader, today announced a strategic partnership to expand access to computational pathology products for clinical and translational research.
By using artificial intelligence to semi-automate the test process, we anticipate it may be easier for results to be delivered to patients faster to better influence treatment decisions. They used samples from a previous trial funded by Cancer Research UK to look at the levels of two proteins, known as AREG and EREG, which are produced by some colorectal cancers. Algorithms driven by AI enabled the researchers to show that patients with higher levels of these proteins received significant benefit from a treatment which inhibits a different protein involved in cancer cell growth, known as EGFR.
The adoption of digital technology in pathology has often been directly compared to radiology. Yet, in 2019 and more than a decade after the first slide scanners were introduced, it was not uncommon to see a conference presentation about regulatory frameworks for clinical use and digital pathology adoption for primary diagnosis. Clearly the barriers to clinical adoption were much higher than anyone had anticipated a decade before.
University of Minnesota Medical School researchers have offered new ways to think about the immune system thanks to a recent study published in Nature. Their research, which indicates organ tissues become increasingly immune throughout life, may begin to alter fundamental ideas regarding the rules of vaccination and the immune system's function within the body.
Digital pathology techniques were developed more than a decade ago and have unquestionably enhanced digital image sharing among collaborating laboratories and pathologists. When compared to the early global adoption of the technology within the research and pharmaceutical sectors, the uptake of digital platforms within routine, clinical pathology has been somewhat measured. Traditional tissue pathology procedures and protocols [...]
Despite rapid technological advances in molecular diagnostics, optical microscopy remains the gold standard in pathology, cancer diagnosis, and disease monitoring. Considering that the optical principles of light microscopy and histological preparation methods have seen little change over decades or even centuries, the development of new microscopy and histological preparation methods seems to be long overdue. Limitations of [...]
