TLS Detect

Set the standard for TLS detection

Detect Tertiary Lymphoid Structures across tumor types from digitized H&E slides

Description
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Gain insights into a tumor’s interaction with the immune system

TLS provide crucial insights to better understand the response to immunotherapies^*

Prognostic role

A major player in antitumor immune response, the presence of TLS has been associated with improved survival in several tumor types.¹

Predictive biomarker

During drug development and clinical trials TLS can serve as a predictive biomarker for response to certain immunotherapies.

Therapeutic target

Presence of TLS potentially indicates an enhanced immune response making it a possible target for improved response to immunotherapy.²

Combination therapies

TLS could guide the development of therapies that target both the tumor cells and the local immune environment.

Trial optimization

TLS can support clinical trial optimization, to help better select trial participants to improve success rates across trial phases.

Gain insights into a tumor’s interaction with the immune system

As a novel biomarker, TLS presence helps stratify the overall survival risk of untreated cancer patients and helps identify those who may benefit from efficient immunotherapy treatment.

Waiv’s simple and standardized approach could support the adoption of this biomarker as an independent predictor of response to immune checkpoint inhibitors (ICI).

With a sensitivity of 97%, TLS Detect supports the screening for TLS presence across tumors within a research setting.