Indica Labs – HALO

The gold standard image analysis platform for quantitative tissue analysis in digital pathology.

Pharmaceutical, healthcare and research organizations worldwide are using HALO for high-throughput, quantitative tissue analysis in oncology, neuroscience, metabolism, toxicology and more.

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Product Description

Scalability coupled with powerful analytic capabilities, and the fastest processing speeds available for digital pathology.

Indica Labs - Digital Pathology

UNMATCHED EASE-OF-USE

HALO modules simplify the analysis workflow so there is no need to ‘build’ algorithms from scratch. Modules make HALO easy-to-use and understand which means you can spend less time learning software and more time analyzing data.

HALO add-ons can be used in combination with any of the other analysis modules to improve the analysis workflow. These include tools to help automate tissue segmentation, such as tissue classifier, serial section analysis, and TMA, as well as tools to improve image processing speeds for high-throughput labs, such as analysis cluster.

EXTENSIVE ANALYTICS

HALO reports morphological and multiplexed expression data on a cell-by-cell basis across entire tissue sections whilst maintaining an interactive link between cell data, including x, y coordinates, and cell image.

Sorting and filtering capabilities allow the user to mine millions of cells while visually assessing corresponding cell populations in the image. For example, sort cells according to biomarker intensity and immediately locate cells with highest intensity in the image.

Indica Labs - Digital Pathology
Indica Labs - Digital Pathology

MULTIPLEX ANALYSIS

The Multiplex IHC module in HALO can analyze up to five chromogenic stains in a section while the Highplex FL module can analyze an unlimited number of markers in fluorescence.

SCALABLE PLATFORM

HALO’s modular design and flexible licensing allow it to be adapted to any requirement and budget. Start with all the modules or just a few and add more modules as your needs change. Use HALO on a single workstation or ramp up to a server-based license for your entire group. Purchase a permanent license or renew annually.

Indica Labs - Digital Pathology

Available HALO Modules

Highly Flexible and Oncology Modules

Indica Labs - Digital Pathology
Tissue Classifier
Indica Labs - Digital Pathology
Object Colocalization
Indica Labs - Digital Pathology
Tissue Microarray (TMA)
Indica - Labs - Digital Pathology
Cytonuclear IHC
Indica Labs - Digital Pathology
Membrane FL
Indica Labs - Digital Pathology
Area Quantification
Indica Labs - Digital Pathology
Object Colocalization FL
Indica Labs - Digital Pathology
Multiplex IHC
Indica Labs - Digital Pathology
Cytonuclear FL
Indica Labs - Digital Pathology
Area Quantification FL
Indica Labs - Digital Pathology
Spatial Analysis
Indica Labs - Digital Pathology
Highplex FL
Indica Labs - Digital Pathology
Membrane IHC

ISH and FISH Modules

Indica Labs - Digital Pathology
FISH-IF (RNAScope®)
Indica Labs - Digital Pathology
Multiplex FISH (RNAScope®)
Indica Labs - Digital Pathology
ISH-IHC (RNAScope®)
Indica Labs - Digital Pathology
Amplification & Deletion FISH
Indica Labs - Digital Pathology
ISH (RNAScope®)
Indica Labs - Digital Pathology
Break Apart Fusion FISH

Other Research Modules

Indica Labs - Digital Pathology
Islet IHC
Indica Labs - Digital Pathology
Muscle Fiber FL
Indica Labs - Digital Pathology
Microglial Activation
Indica Labs - Digital Pathology
Analysis Cluster Add-on
Indica Labs - Pathology News
Islet FL
Indica Labs - Digital Pathology
Vacuole
Indica Labs - Digital Pathology
Branch Structure
Indica Labs - Digital Pathology
Muscle Fiber
Indica Labs - Digital Pathology
Axon
Indica Labs - Digital Pathology
Serial Section Analysis

More Solutions from Indica Labs

Additional Information

Clinical | Research Suitability

Research

Imaging Modality Supported

Brightfield, Fluorescence, IMC, MIBI

User Customizable | Application-Specific Algorithms

Application Specific, User customizable

Max No. Multiplexed Biomarkers

>50 Biomarkers, Multiplex up to 5 brightfield markers, unlimited FL and FISH multiplex

Supported Assay Types

Chromogenic in situ hybridization (CISH), Fluorescence in situ hybridization (FISH), Hematoxylin & Eosin (H&E), Immunofluorescence, Immunohistochemistry (IHC), Multiplexing (> 7 Markers), Special Stains

Research Use Only Applications

User Customizable Algorithms Suitable for Multiple Applications

On-Premise Deployment

yes

Cloud Deployment

yes

TMA Support

yes

File Formats Produced | Supported

.png, .svs, 3DHistech .mrxs, Akoya .qptiff, DICOM, Hamamatsu .ndpi, Hamamatsu .ndpis, Huron .svs, Huron .tif, JP2, JPEG/JPG/JPEG 2000, Leica .afi, Leica .lif, Leica .scn, Leica .svs, Leica Aperio .ome-tif, Leica Aperio .svs, Mikroscan .svs, Mikroscan .tif, Motic .svs, Motic .tif, Nikon .nd2, Objective Imaging .svs, Olympus .vsi, OptraSCAN .jp2, Philips .iSyntax, Philips .tiff, Roche .tif, TIFF/TIF, Ventana .bif, Zeiss .czi, KFBIO.kfb, Trestle .tif, Whole Slide Images (WSI)

Additional Notes*

All modules enable the user to optimize analysis settings for their specific images., HALO modules range from highly flexible options, such as Highplex FL and Multiplex IHC, used across a range of applications to more specialized modules like Microglial Activation., The HALO TMA add-on can be used in conjunction with cell-based analysis modules as well as the HALO Tissue Classifier add-on., The HALO TMA add-on enables automated, high-throughput segmentation and batch analysis of whole slide TMA images.

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HALO Brochure

HALO Brochure



Application Note 1

Application Note 1



Application Note 2

Application Note 2



Lunaphore eBook

Lunaphore eBook



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