The Ki-67 protein is associated with cellular proliferation and can be assessed by Ki-67-immunohistochemical (IHC) staining. The calculated proliferation index can be correlated to the tumor grade and the clinical course.

The Ki-67 solution is fully automated and does not require manual input during analysis. The solution consists of four automated analysis steps. Once started, it automatically separates the sample tissue from control tissues and robustly identifies invasive cancer areas in the sample. Tumor nuclei are counted based on their Ki-67 expression and the resulting proliferation index for the whole tumor area is calculated.