Owkin is proud to announce its participation in the 11th Digital Pathology & AI Congress: Europe, scheduled for December 11–12, 2024, at the Hilton London Metropole in London, UK. This esteemed event will convene leading professionals to explore the latest advancements in digital pathology and artificial intelligence.

As part of this prestigious event, Owkin will deliver a presentation showcasing its innovative contributions to digital pathology and artificial intelligence. Attendees are also invited to visit Owkin at Booth #11 to learn more about their cutting-edge solutions and engage with their team of experts.”Don’t miss Owkin’s presentation!

• Date: Wednesday, December 11

• Time: 3:40-3:55pm
• Track: Pharma/Biotech Case Studies
• Presentation title: AI for histology-based spatial biomarker discovery

Abstract:

• Understanding the tumor microenvironment (TME) and its spatial architecture is crucial for enhancing patient outcomes. However, research has been hindered by the absence of standardized quantification methods. At Owkin, we address this by developing HistoPLUS, a suite of reproducible AI-based biomarkers, to accurately characterize patients’ TMEs.

Our presentation will outline methodologies for characterizing individual patients’ TMEs at the cellular level. We employ active learning techniques and collaborate with data scientists and pathologists to create high-quality datasets and robust cell-level detection and classification models.

These models generate spatially resolved characterizations of patient tumors. For example, we demonstrate that the density of lymphocytes within the tumor core, along with metrics quantifying their spatial organization, are significant prognostic factors in colorectal and breast cancer.

These spatial descriptors are integrated into our drug discovery engines to refine and optimize patient population selection for therapeutic development.

Speaker:

Aurélie Fugon

Business Development Director

Biomarker and Discovery Pharma Solutions

Owkin